MK-2894 - CAS# 1006036-87-8 60290 adavosertib

adavosertib

Su-11274 exhibits a selective inhibition pattern toward different receptor mutated variants

36)32-20-31/h2-17

Akts are anti-apoptotic serine/theronine-specific protein kinases that phosphorylate and inactivate components of the apoptotic machinery

also known as BHG-712

MK-2894 - CAS# 1006036-87-8 60290 adavosertibMK 2894 is a potent and selective prostaglandin E2 subtype 4 receptor (PGE2) antagonist. MK 2894 exhibits favorable pharmacokinetic profile in a number of preclinical species and potent anti inflammatory activity in several animal models of pain inflammation. MK 2894 also shows favorable GI tolerability profile in rats when compared to traditional NSAID indomethacin. Product information CAS Number: 1006036 87 8 Molecular Weight: 473. 51 Formula: