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Marijuana and hashish are usually smoked but may be also eaten or used in a tea form (Ashton, 2001)

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Binding of -MSH/ACTH to MC1R activates adenylate cyclase (AC), which catalyses the production of the secondary messenger cAMP [32]

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The foot processes (FP) of podocytes are lost or fused, which leads to podocyte hypertrophy and reduced levels of podocyte-related proteins, such as nephrin and podocin ( 2.3 Renal impairment Oxidative stress-induced kidney damage includes direct and indirect mechanisms