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Theoretical concerns about excessive neuroplasticity or uncontrolled growth factor signaling remain unresolved

Inflammation: The body's immune system responds to the bacterial overgrowth, leading to the red, swollen, and painful lesions we know as pimples, cysts, and nodules

Y.ChaeS.ChoiS.MoonJ.KimM.et al (2021)

Based on these historical events, newly developed anti-obesity drugs should have proven safety and/or efficacy on cardiovascular events in addition to its weight loss effect