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Additionally, for the organic acidemias, methylmalonic and propionic acidemia (OMIM 251000 and 606054, respectively), monthly prophylactic treatment with the antibiotic metronidazole is also commonly used to reduce intestinal bacteria and the affiliated production of propionate, and this may confer the unexpected benefit of reducing TMAO production as well (Thompson et al

For in vivo metabolic analysis, mice were intraperitoneally injected with a 15 N-glutamine solution (40 mg/kg in PBS)

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doi: 10.1038/bjc.2011.83 241 Andrade-VieiraRXuZColpPMarignaniPA

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coli , mammalian cells and cell-free systems