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The Synergistic Triple-Pathway Effect The simultaneous activation of all three receptors creates a metabolic cascade that no single or dual agonist can replicate: reduced calorie intake + increased energy output + improved glycemic control, all at once

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[DOI] [PMC free article] [PubMed] [Google Scholar] 4.Wang J.Y., Wang Q.W., Yang X.Y., Yang W., Li D.R., Jin J.Y., Zhang H.C., Zhang X.F

It functions by mimicking two key hormones glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), which are released by the intestines after eating

The lipid-modifying effects should be considered as part of a broader cardiometabolic benefit profile rather than a primary indication for cholesterol management

Magnesium also plays a critical role in glucose metabolism and insulin sensitivity